are some people resistant to glp 1 GLP-1 receptor agonists Do GLP-1s cause people to

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PubMed 79

Tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) activates two receptors GLP-1 and GIP which is why it tends to produce somewhat stronger weight-loss results on average

Jena, MD PhD Department of Health Care Policy, Harvard Medical School , Boston, MA Department of Medicine, Massachusetts General Hospital , Boston, MA National Bureau of Economic Research , Cambridge, MA, Nicholas Stucky, MD PhD Truveta, Inc , Bellevue, WA With the growing popularity of GLP-1 RAs, concerns have been raised that the expanded use may occur amongst patients with less clinical need